Accioly MT, Pacheco P, Maya-Monteiro CM, Carrossini N, Robbs BK, Oliveira SS et al (2008) Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells. Cancer Res 68(6):1732–1740. https://doi.org/10.1158/0008-5472.CAN-07-1999

Article  CAS  PubMed  Google Scholar 

Aisenberg AC (1961) The Glycolysis and Respiration of Tumors. Academic Press, New York

Google Scholar 

Akgoc Z, Mukherjee P, Seyfried TN (2022) The Glucose Ketone Index predicts overall survival and metastasis of mouse tumor cells to visceral organs and brain. Long Chin Med 5:1–11. https://doi.org/10.21037/lcm-21-43

Article  Google Scholar 

Alcala S, Villarino L, Ruiz-Canas L, Couceiro JR, Martinez-Calvo M, Palencia-Campos A et al (2024) Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy. J Exp Clin Cancer Res 43(1):33. https://doi.org/10.1186/s13046-023-02931-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alcazar-Fabra M, Navas P, Brea-Calvo G (2016) Coenzyme Q biosynthesis and its role in the respiratory chain structure. Biochim Biophys Acta 1857(8):1073–1078. https://doi.org/10.1016/j.bbabio.2016.03.010

Article  CAS  PubMed  Google Scholar 

Andrews PA, Albright KD (1992) Mitochondrial defects in cis-diamminedichloroplatinum(II)-resistant human ovarian carcinoma cells. Cancer Res 52(7):1895–901. https://www.ncbi.nlm.nih.gov/pubmed/1551118. Accessed 7 Jan 2025

Arciuch VGA, Elguero ME, Poderoso JJ, Carreras MC (2012) Mitochondrial Regulation of Cell Cycle and Proliferation. Antioxid Redox Signal 16(10):1150–1180. https://doi.org/10.1089/ars.2011.4085

Article  CAS  Google Scholar 

Arcos JC, Tison MJ, Gosch HH, Fabian JA (1969) Sequential alterations in mitochondrial inner and outer membrane electron transport and in respiratory control during feeding of amino azo dyes; stability of phosphorylation. Correlation with swelling-contraction changes and tumorigenesis threshold. Cancer Res 29(6):1298–305. http://www.ncbi.nlm.nih.gov/pubmed/4307786. Accessed 7 Jan 2025

Arismendi-Morillo G, Hoa NT, Ge L, Jadus MR (2012) Mitochondrial network in glioma’s invadopodia displays an activated state both in situ and in vitro: potential functional implications. Ultrastruct Pathol 36(6):409–414. https://doi.org/10.3109/01913123.2012.694582

Article  PubMed  Google Scholar 

Arismendi-Morillo G, Castellano-Ramirez A, Seyfried TN (2017) Ultrastructural characterization of the Mitochondria-associated membranes abnormalities in human astrocytomas: Functional and therapeutics implications. Ultrastruct Pathol 41(3):234–244. https://doi.org/10.1080/01913123.2017.1300618

Article  PubMed  Google Scholar 

Arismendi-Morillo GJ, Castellano-Ramirez AV (2008) Ultrastructural mitochondrial pathology in human astrocytic tumors: potentials implications pro-therapeutics strategies. J Electron Microsc (Tokyo) 57(1):33–9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18230641. Accessed 7 Jan 2025

Arismendi-Morillo G (2011) Electron microscopy morphology of the mitochondrial network in gliomas and their vascular microenvironment (Research Support, Non-U.S. Gov't Review). Biochimica et biophysica acta 1807(6):602–8. http://www.ncbi.nlm.nih.gov/pubmed/21692239. Accessed 7 Jan 2025

Auger C, Vinaik R, Appanna VD, Jeschke MG (2021) Beyond mitochondria: Alternative energy-producing pathways from all strata of life. Metabolism 118:154733. https://doi.org/10.1016/j.metabol.2021.154733

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baker SG (2015) A cancer theory kerfuffle can lead to new lines of research. J Natl Cancer Inst 107(2). https://doi.org/10.1093/jnci/dju405

Bartesaghi S, Graziano V, Galavotti S, Henriquez NV, Betts J, Saxena J et al (2015) Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells. Proc Natl Acad Sci U S A 112(4):1059–1064. https://doi.org/10.1073/pnas.1413165112

Article  CAS  PubMed  PubMed Central  Google Scholar 

Battino M, Fato R, Parenti-Castelli G, Lenaz G (1990) Coenzyme Q can control the efficiency of oxidative phosphorylation. Int J Tissue React 12(3):137–44. https://www.ncbi.nlm.nih.gov/pubmed/2276890. Accessed 7 Jan 2025

Bayley JP, Devilee P (2010) Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Barking up the right tree? Curr Opin Genet Dev 20(3):324–9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20304625. Accessed 7 Jan 2025

Begriche K, Massart J, Robin MA, Bonnet F, Fromenty B (2013) Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease. Hepatology 58(4):1497–1507. https://doi.org/10.1002/hep.26226

Article  CAS  PubMed  Google Scholar 

Bell JA (1998) Overcoming dogma in epistemology. Issues Integrative Studies 16:99–119

Google Scholar 

Bhargava P, Schnellmann RG (2017) Mitochondrial energetics in the kidney. Nat Rev Nephrol 13(10):629–646. https://doi.org/10.1038/nrneph.2017.107

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhatia B, Hsieh M, Kenney AM, Nahle Z (2011) Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma. Oncogene 30(4):410–422. https://doi.org/10.1038/onc.2010.454

Article  CAS  PubMed  Google Scholar 

Birsoy K, Wang T, Chen WW, Freinkman E, Abu-Remaileh M, Sabatini DM (2015) An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis. Cell 162(3):540–551. https://doi.org/10.1016/j.cell.2015.07.016

Article  CAS  PubMed  PubMed Central  Google Scholar 

Biswas G, Srinivasan S, Anandatheerthavarada HK, Avadhani NG (2008) Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signaling. Proc Natl Acad Sci U S A 105(1):186–191. https://doi.org/10.1073/pnas.0706183104

Article  PubMed  PubMed Central  Google Scholar 

Bloch-Frankenthal L, Langan J, Morris HP, Weinhouse S (1965) Fatty acid oxidation and ketogenesis in transplantable liver tumors. Cancer Res 25:732–6

CAS  PubMed  Google Scholar 

Bochud-Allemann N, Schneider A (2002) Mitochondrial substrate level phosphorylation is essential for growth of procyclic Trypanosoma brucei. J Biol Chem 277(36):32849–32854. https://doi.org/10.1074/jbc.M205776200

Article  CAS  PubMed  Google Scholar 

Boros LG, Lee PW, Brandes JL, Cascante M, Muscarella P, Schirmer WJ et al (1998) Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism? Med Hypotheses 50(1):55–9. https://www.ncbi.nlm.nih.gov/pubmed/9488183. Accessed 7 Jan 2025

Borrego SL, Fahrmann J, Hou J, Lin DW, Tromberg BJ, Fiehn O et al (2021) Lipid remodeling in response to methionine stress in MDA-MBA-468 triple-negative breast cancer cells. J Lipid Res 62:100056. https://doi.org/10.1016/j.jlr.2021.100056

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bosc C, Broin N, Fanjul M, Saland E, Farge T, Courdy C et al (2020) Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites. Nat Commun 11(1):4056. https://doi.org/10.1038/s41467-020-17882-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boulton DP, Caino MC (2022) Mitochondrial Fission and Fusion in Tumor Progression to Metastasis. Front Cell Dev Biol 10:849962. https://doi.org/10.3389/fcell.2022.849962

Article  PubMed  PubMed Central  Google Scholar 

Brand MD, Couture P, Else PL, Withers KW, Hulbert AJ (1991) Evolution of energy metabolism. Proton permeability of the inner membrane of liver mitochondria is greater in a mammal than in a reptile. Biochem J, 275 ( Pt 1):81–6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1850242. Accessed 7 Jan 2025

Brand MD, Nicholls DG (2011) Assessing mitochondrial dysfunction in cells. Biochem J 435(2):297–312. https://doi.org/10.1042/BJ20110162

Article  CAS  PubMed  Google Scholar 

Brawn PN, Mackay B (1980) Intracristal crystalline inclusions in mitochondria of a neuroblastoma. Ultrastruct Pathol 1(4):495–7. https://www.ncbi.nlm.nih.gov/pubmed/6100839. Accessed 7 Jan 2025

Brown LJ, Aparicio SR (1984) Malignant Warthin’s tumour: an ultrastructural study. J Clin Pathol 37(2):170–175. https://doi.org/10.1136/jcp.37.2.170

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brucher BL, Jamall IS (2016) Somatic Mutation Theory - Why it’s Wrong for Most Cancers. Cell Physiol Biochem 38(5):1663–1680. https://doi.org/10.1159/000443106

Article  CAS  PubMed  Google Scholar 

Bundtzen JL, Norback DH (1982) The ultrastructure of poorly differentiated rhabdomyosarcomas: a case report and literature review. Hum Pathol 13(4):301–13. https://www.ncbi.nlm.nih.gov/pubmed/7076215. Accessed 7 Jan 2025

Burgess S, Foley CN, Zuber V (2018) Inferring causal relationships between risk factors and outcomes from genome-wide association study data. Annu Rev Genomics Hum Genet 19:303–327. https://doi.org/10.1146/annurev-genom-083117-021731

Article  CAS  PubMed  PubMed Central  Google Scholar 

Burk D, Woods M, Hunter J (1967) On the significance of glucolysis for cancer growth, with special reference to Morris rat hepatomas. J Natl Cancer Inst 38(6):839–63. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4381692. Accessed 7 Jan 2025

Burk D, Schade AL (1956) On respiratory impairment in cancer cells. Science 124:270–72