Bridges MC, Daulagala AC, Kourtidis A (2021) LNCcation: LncRNA localization and function. J Cell Biol 220(2)

Cao J, Zhao Q, Jia Q, Li Y (2023a) LncRNA-CBR3-AS1 promotes and enhances the malignancy of ulcerative colitis via targeting miRNA-145-5p/FN1. Cell Mol Biol (Noisy-le-grand) 69(7):181–186

Article  PubMed  Google Scholar 

Cao L, Tan Q, Zhu R, Ye L, Shi G, Yuan Z (2023b) LncRNA MIR4435-2HG suppression regulates macrophage M1/M2 polarization and reduces intestinal inflammation in mice with ulcerative colitis. Cytokine 170:156338.

Chen K, Shang S, Yu S, Cui L, Li S, He N (2022) Identification and exploration of Pharmacological pyroptosis-related biomarkers of ulcerative colitis. Front Immunol 13:998470

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen B, Dong X, Zhang JL, Sun X, Zhou L, Zhao K, Deng H, Sun Z (2024) Natural compounds target programmed cell death (PCD) signaling mechanism to treat ulcerative colitis: a review. Front Pharmacol 15:1333657

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guide for the (2011) Care and Use of Laboratory Animals. 8th ed. Washington (DC)

Han J, Li Y, Zhang B, Liu H, Wu M, Zhang X (2020) LncRNA TUG1 regulates ulcerative colitis through miR-142-5p/SOCS1 axis. Microb Pathog 143:104139

Article  CAS  PubMed  Google Scholar 

Jin H, Zhu Y, Wang XD, Luo EF, Li YP, Wang BL, Chen YF (2021) BDNF corrects NLRP3 inflammasome-induced pyroptosis and glucose metabolism reprogramming through KLF2/HK1 pathway in vascular endothelial cells. Cell Signal 78:109843

Article  CAS  PubMed  Google Scholar 

Khan I, Oriowo MA, Anim JT (2005) Amelioration of experimental colitis by Na-H exchanger-1 inhibitor Amiloride is associated with reversal of IL-1ss and ERK mitogen-activated protein kinase. Scand J Gastroenterol 40(5):578–585

Article  CAS  PubMed  Google Scholar 

Kobayashi T, Siegmund B, Le Berre C, Wei SC, Ferrante M, Shen B, Bernstein CN, Danese S, Peyrin-Biroulet L, Hibi T (2020) Ulcerative colitis. Nat Rev Dis Primers 6(1):74

Article  PubMed  Google Scholar 

Le Berre C, Honap S, Peyrin-Biroulet L (2023) Ulcerative colitis. Lancet 402(10401):571–584

Article  PubMed  Google Scholar 

Liu S, Zhang S, Lv X, Lu J, Ren C, Zeng Z, Zheng L, Zhou X, Fu H, Zhou D et al (2019) Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway. Int Immunopharmacol 75:105768

Article  CAS  PubMed  Google Scholar 

Liu J, Li Z, Yu G, Wang T, Qu G, Wang Y (2021) LINC01232 promotes gastric cancer proliferation through interacting with EZH2 to inhibit the transcription of KLF2. J Microbiol Biotechnol 31(10):1358–1365

Article  CAS  PubMed  PubMed Central  Google Scholar 

Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta delta C(T)) method. Methods 25(4):402–408

Article  CAS  PubMed  Google Scholar 

Ma S, Yang B, Du Y, Lv Y, Liu J, Shi Y, Huang T, Xu H, Deng L, Chen X (2023) 1,8-cineole ameliorates colon injury by downregulating macrophage M1 polarization via inhibiting the HSP90-NLRP3-SGT1 complex. J Pharm Anal 13(9):984–998

Article  PubMed  PubMed Central  Google Scholar 

Mas-Ponte D, Carlevaro-Fita J, Palumbo E, Hermoso Pulido T, Guigo R, Johnson R (2017) LncATLAS database for subcellular localization of long noncoding RNAs. RNA 23(7):1080–1087

Article  CAS  PubMed  PubMed Central  Google Scholar 

Muppirala UK, Honavar VG, Dobbs D (2011) Predicting RNA-protein interactions using only sequence information. BMC Bioinformatics 12:489

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rao J, Shao L, Lin M, Huang J, Fan L (2021) LncRNA UCA1 accelerates the progression of ulcerative colitis via mediating the miR-331-3p/BRD4 axis. Int J Gen Med 14:2427–2435

Article  PubMed  PubMed Central  Google Scholar 

Rao Z, Zhu Y, Yang P, Chen Z, Xia Y, Qiao C, Liu W, Deng H, Li J, Ning P et al (2022) Pyroptosis in inflammatory diseases and cancer. Theranostics 12(9):4310–4329

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D et al (2024) JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res 52(D1):D174–D182

Article  CAS  PubMed  Google Scholar 

Thakar S, Katakia YT, Ramakrishnan SK, Pandya Thakkar N, Majumder S (2021) Intermittent high glucose elevates nuclear localization of EZH2 to cause H3K27me3-Dependent repression of KLF2 leading to endothelial inflammation. Cells 10(10)

Tian Y, Cui L, Lin C, Wang Y, Liu Z, Miao X (2020) LncRNA CDKN2B-AS1 relieved inflammation of ulcerative colitis via sponging miR-16 and miR-195. Int Immunopharmacol 88:106970

Article  CAS  PubMed  Google Scholar 

Turpaev KT (2020) Transcription factor KLF2 and its role in the regulation of inflammatory processes. Biochem (Mosc) 85(1):54–67

Article  CAS  Google Scholar 

Ungaro R, Mehandru S, Allen PB, Peyrin-Biroulet L, Colombel JF (2017) Ulcerative colitis. Lancet 389(10080):1756–1770

Article  PubMed  Google Scholar 

Wang ZL, Wang YD, Wang K, Li JA, Li L (2018) KFL2 participates in the development of ulcerative colitis through inhibiting inflammation via regulating cytokines. Eur Rev Med Pharmacol Sci 22(15):4941–4948

PubMed  Google Scholar 

Wang Y, Wang N, Cui L, Li Y, Cao Z, Wu X, Wang Q, Zhang B, Ma C, Cheng Y (2021) Long Non-coding RNA MEG3 alleviated ulcerative colitis through upregulating miR-98-5p-Sponged IL-10. Inflammation 44(3):1049–1059

Article  CAS  PubMed  Google Scholar 

Xu G, Fu S, Zhan X, Wang Z, Zhang P, Shi W, Qin N, Chen Y, Wang C, Niu M et al (2021) Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90. JCI Insight 6(2)

Yan R, Liang X, Hu J (2023) miR-141-3p alleviates ulcerative colitis by targeting SUGT1 to inhibit colonic epithelial cell pyroptosis. Autoimmunity 56(1):2220988

Article  PubMed  Google Scholar 

Ye B, Lu Z (2022) Role of TRIM22 in ulcerative colitis and its underlying mechanisms. Mol Med Rep 26(2)

Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD (2010) The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 32(3):379–391

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao X, Cui DJ, Yang LC, Yuan WQ, Yan F (2022) Long noncoding RNA FBXL19-AS1-Mediated ulcerative Colitis-Associated intestinal epithelial barrier defect. Tissue Eng Regen Med 19(5):1077–1088

Article  CAS  PubMed  PubMed Central  Google Scholar