Siegel L, Vandenakker-Albanese C, Siegel D. Anterior cruciate ligament injuries: anatomy, physiology, biomechanics, and management. Clin J Sport Med Off J Can Acad Sport Med. 2012;22:349–55.
Hoogeslag RAG, Brouwer RW, Boer BC, de Vries AJ, Huis In ’t Veld R. Acute Anterior Cruciate Ligament Rupture: Repair or Reconstruction? Two-Year Results of a Randomized Controlled Clinical Trial. Am J Sports Med. 2019;47:567–77.
Gupta R, Malhotra A, Sood M, Masih GD. Is anterior cruciate ligament graft rupture (after successful anterior cruciate ligament reconstruction and return to sports) actually a graft failure or a re-injury? J Orthop Surg Hong Kong. 2019;27:2309499019829625.
Kaeding CC, Léger-St-Jean B, Magnussen RA. Epidemiology and Diagnosis of Anterior Cruciate Ligament Injuries. Clin Sports Med. 2017;36:1–8.
Vavken P, Murray MM. The potential for primary repair of the ACL. Sports Med Arthrosc Rev. 2011;19:44–9.
Article PubMed PubMed Central Google Scholar
Musahl V, Engler ID, Nazzal EM, Dalton JF, Lucidi GA, Hughes JD, et al. Current trends in the anterior cruciate ligament part II: evaluation, surgical technique, prevention, and rehabilitation. Knee Surg Sports Traumatol Arthrosc. 2022;30:34–51.
Marieswaran M, Jain I, Garg B, Sharma V, Kalyanasundaram D. A review on biomechanics of anterior cruciate ligament and materials for reconstruction. Appl Bionics Biomech. 2018;2018:4657824.
Article PubMed PubMed Central Google Scholar
Malige A, Baghdadi S, Hast MW, Schmidt EC, Shea KG, Ganley TJ. Biomechanical properties of common graft choices for anterior cruciate ligament reconstruction: a systematic review. Clin Biomech Bristol Avon. 2022;95: 105636.
Kraeutler MJ, Wolsky RM, Vidal AF, Bravman JT. Anatomy and biomechanics of the native and reconstructed anterior cruciate ligament: surgical implications. J Bone Joint Surg Am. 2017;99:438–45.
Seijas R, Rius M, Ares O, García-Balletbó M, Serra I, Cugat R. Healing of donor site in bone-tendon-bone ACL reconstruction accelerated with plasma rich in growth factors: a randomized clinical trial. Knee Surg Sports Traumatol Arthrosc. 2015;23:991–7.
Kanazawa T, Soejima T, Noguchi K, Tabuchi K, Noyama M, Nakamura K-I, et al. Tendon-to-bone healing using autologous bone marrow-derived mesenchymal stem cells in ACL reconstruction without a tibial bone tunnel-A histological study-. Muscles Ligaments Tendons J. 2014;4:201–6.
Article PubMed PubMed Central Google Scholar
Li Y, Fu SC, Cheuk YC, Song G, Feng H, Yung S-H. The non-reconstructive treatment of complete ACL tear with biological enhancement in clinical and preclinical studies: A systematic review. Asia-Pac J Sports Med Arthrosc Rehabil Technol. 2018;14:10–6.
PubMed PubMed Central Google Scholar
Andersen RB, Gormsen J. Fibrin dissolution in synovial fluid. Scand J Rheumatol. 1987;16:319–33.
Murray MM, Martin SD, Martin TL, Spector M. Histological changes in the human anterior cruciate ligament after rupture. J Bone Joint Surg Am. 2000;82:1387–97.
Murray MM, Spindler KP, Ballard P, Welch TP, Zurakowski D, Nanney LB. Enhanced histologic repair in a central wound in the anterior cruciate ligament with a collagen-platelet-rich plasma scaffold. J Orthop Res Off Publ Orthop Res Soc. 2007;25:1007–17.
Murray MM, Fleming BC. Biology of anterior cruciate ligament injury and repair: Kappa delta ann doner vaughn award paper 2013. J Orthop Res Off Publ Orthop Res Soc. 2013;31:1501–6.
Andrish J, Holmes R. Effects of synovial fluid on fibroblasts in tissue culture. Clin Orthop. 1979;279–83.
Perrone GS, Proffen BL, Kiapour AM, Sieker JT, Fleming BC, Murray MM. Bench-to-bedside: Bridge-enhanced anterior cruciate ligament repair. J Orthop Res Off Publ Orthop Res Soc. 2017;35:2606–12.
BEAR-MOON Design Group, Spindler KP, Imrey PB, Yalcin S, Beck GJ, Calbrese G, et al. Design Features and Rationale of the BEAR-MOON (Bridge-Enhanced ACL Restoration Multicenter Orthopaedic Outcomes Network) Randomized Clinical Trial. Orthop J Sports Med. 2022;10:23259671211065447.
Murray MM, Fleming BC. Use of a bioactive scaffold to stimulate anterior cruciate ligament healing also minimizes posttraumatic osteoarthritis after surgery. Am J Sports Med. 2013;41:1762–70.
Article PubMed PubMed Central Google Scholar
Vavken P, Fleming BC, Mastrangelo AN, Machan JT, Murray MM. Biomechanical outcomes after bioenhanced anterior cruciate ligament repair and anterior cruciate ligament reconstruction are equal in a porcine model. Arthroscopy. 2012;28:672–80.
Article PubMed PubMed Central Google Scholar
Joshi SM, Mastrangelo AN, Magarian EM, Fleming BC, Murray MM. Collagen-platelet composite enhances biomechanical and histologic healing of the porcine anterior cruciate ligament. Am J Sports Med. 2009;37:2401–10.
Article PubMed PubMed Central Google Scholar
Kiapour AM, Ecklund K, Murray MM, BEAR Trial Team, Flutie B, Freiberger C, et al. Changes in Cross-sectional Area and Signal Intensity of Healing Anterior Cruciate Ligaments and Grafts in the First 2 Years After Surgery. Am J Sports Med. 2019;47:1831–43.
Micheli LJ, Flutie B, Fleming BC, Murray MM. Bridge-enhanced ACL Repair: Mid-term Results of the First-in-human Study. Orthop J Sports Med. 2017;5:2325967117S00305.
Murray MM, Flutie BM, Kalish LA, Ecklund K, Fleming BC, Proffen BL, et al. The Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) Procedure. Orthop J Sports Med. 2016;4:2325967116672176.
Article PubMed PubMed Central Google Scholar
Murray MM, Kalish LA, Fleming BC, Flutie B, Freiberger C, Henderson RN, et al. Bridge-Enhanced Anterior Cruciate Ligament Repair: Two-Year Results of a First-in-Human Study. Orthop J Sports Med. 2019;7:2325967118824356.
Article PubMed PubMed Central Google Scholar
Barnett S, Murray MM, Liu S, BEAR Trial Team, Micheli LJ. Resolution of Pain and Predictors of Postoperative Opioid use after Bridge-Enhanced Anterior Cruciate Ligament Repair and Anterior Cruciate Ligament Reconstruction. Arthrosc Sports Med Rehabil. 2020;2:e219–28.
Barnett SC, Murray MM, Badger GJ, BEAR Trial Team, Yen Y-M, Kramer DE, et al. Earlier Resolution of Symptoms and Return of Function After Bridge-Enhanced Anterior Cruciate Ligament Repair As Compared With Anterior Cruciate Ligament Reconstruction. Orthop J Sports Med. 2021;9:23259671211052530.
Freiberger C, Kiapour AM, Liu S, BEAR Trial Team, Henderson RN, Barnett S, et al. Higher physiologic platelet counts in whole blood are not associated with improved ACL cross-sectional area or signal intensity 6 months after bridge-enhanced ACL repair. Orthop J Sports Med. 2020;8:2325967120927655.
Barnett S, Badger GJ, Kiapour A, Yen Y-M, Henderson R, Freiberger C, et al. Females have earlier muscle strength and functional recovery after bridge-enhanced anterior cruciate ligament repair. Tissue Eng Part A. 2020;26:702–11.
Article PubMed PubMed Central Google Scholar
Murray MM, Fleming BC, Badger GJ, Freiberger C, Henderson R, Barnett S, et al. Bridge-enhanced anterior cruciate ligament repair is not inferior to autograft anterior cruciate ligament reconstruction at 2 years: results of a prospective randomized clinical trial. Am J Sports Med. 2020;48:1305–15.
Article PubMed PubMed Central Google Scholar
Murray MM, Kiapour AM, Kalish LA, Ecklund K, BEAR Trial Team, Freiberger C, et al. Predictors of healing ligament size and magnetic resonance signal intensity at 6 months after bridge-enhanced anterior cruciate ligament repair. Am J Sports Med. 2019;47:1361–9.
Sanborn RM, Badger GJ, BEAR Trial Team, Yen Y-M, Murray MM, Christino MA, et al. Psychological readiness to return to sport at 6 months is higher after bridge-enhanced acl restoration than autograft acl reconstruction: results of a prospective randomized clinical trial. Orthop J Sports Med. 2022;10:23259671211070542.
Barnes DA, Flannery SW, Badger GJ, Yen Y-M, Micheli LJ, Kramer DE, et al. Quantitative MRI biomarkers to predict risk of reinjury within 2 years after bridge-enhanced acl restoration. Am J Sports Med. 2023;51:413–21.
Article PubMed PubMed Central Google Scholar
Flannery SW, Murray MM, Badger GJ, Ecklund K, BEAR Trial Team, Kramer DE, et al. Early MRI-based quantitative outcomes are associated with a positive functional performance trajectory from 6 to 24 months post-ACL surgery. Knee Surg Sports Traumatol Arthrosc. 2023;31:1690–8.
Menghini D, Kaushal SG, Flannery SW, Ecklund K, Murray MM, Fleming BC, et al. Changes in the cross-sectional profile of treated anterior cruciate ligament within 2 years after surgery. Orthop J Sports Med. 2022;10:23259671221127330.
Article PubMed PubMed Central Google Scholar
Kiapour AM, Flannery SW, Murray MM, Miller PE, BEAR Trial Team, Proffen BL, et al. Regional differences in anterior cruciate ligament signal intensity after surgical treatment. Am J Sports Med. 2021;49:3833–41.
Sanborn RM, Badger GJ, Fleming BC, Kiapour AM, BEAR Trial Team, Fadale PD, et al. Preoperative risk factors for subsequent ipsilateral acl revision surgery after an ACL restoration procedure. Am J Sports Med. 2023;51:49–57.
Shah AK, Rizy ME, Neijna AG, Uppstrom TJ, Gomoll AH, Strickland SM. A preliminary study of post-market bridge-enhanced ACL restoration (BEAR) suggests non-inferior short-term outcomes and low complications. HSS J. 2024;15563316241265351.
Gao S, Wang T. Suture anchor technique for bridge enhanced anterior cruciate ligament restoration. Arthrosc Tech [Internet]. 2024 [cited 2024 May 30];13. Available from: https://www.arthroscopytechniques.org/article/S2212-6287(23)00342-0/fulltext.
Sherman SL, Copeland ME, Milles JL, Flood DA, Pfeiffer FM. Biomechanical evaluation of suture anchor versus transosseous tunnel quadriceps tendon repair techniques. Arthrosc J Arthrosc Relat Surg Off Publ Arthrosc Assoc N Am Int Arthrosc Assoc. 2016;32:1117–24.
Muench LN, Berthold DP, Archambault S, Slater M, Mehl J, Obopilwe E, et al. Anterior cruciate ligament (ACL) repair using cortical or anchor fixation with suture tape augmentation vs ACL reconstruction: A comparative biomechanical analysis. Knee. 2022;34:76–88.
Rehabilitation Protocol | Miach Orthopaedics [Internet]. [cited 2024 May 19]. Available from: https://miachortho.com/healthcare-professionals/rehabilitation-protocol/.
Kaeding CC, Aros B, Pedroza A, Pifel E, Amendola A, Andrish JT, et al. Allograft versus autograft anterior cruciate ligament reconstruction. Sports Health. 2011;3:73–81.
Article PubMed PubMed Central Google Scholar
Borchers JR, Pedroza A, Kaeding C. Activity level and graft type as risk factors for anterior cruciate ligament graft failure: a case-control study. Am J Sports Med. 2009;37:2362–7.
Spindler KP, Parker RD, Andrish JT, Kaeding CC, Wright RW, Marx RG, et al. Prognosis and predictors of ACL reconstructions using the MOON cohort: a model for comparative effectiveness studies. J Orthop Res. 2013;31:2–9.
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