Ali MM, Mahmoud AM, Le Master E, Levitan I, Phillips SA (2019) Role of matrix metalloproteinases and histone deacetylase in oxidative stress-induced degradation of the endothelial glycocalyx. Am J Physiol Heart Circ Physiol 316:H647–H663. https://doi.org/10.1152/ajpheart.00090.2018

Article  PubMed  PubMed Central  CAS  Google Scholar 

Al-Maghrabi J (2021) Loss of expression of syndecan-1 is associated with tumor recurrence, metastatic potential, and poor survival in patients with colorectal carcinoma. Pak J Med Sci 37:114–120. https://doi.org/10.12669/pjms.37.1.2592

Article  PubMed  PubMed Central  Google Scholar 

Aquino RS, Teng YH, Park PW (2018) Glycobiology of syndecan-1 in bacterial infections. Biochem Soc Trans 46:371–377. https://doi.org/10.1042/BST20170395

Article  PubMed  PubMed Central  CAS  Google Scholar 

Arnold K, Xu Y, Sparkenbaugh EM, Li M, Han X, Zhang X, Xia K, Piegore M, Zhang F, Zhang X, Henderson M, Pagadala V, Su G, Tan L, Park PW, Stravitz RT, Key NS, Linhardt RJ, Pawlinski R, Xu D, Liu J (2020) Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure. Sci Transl Med 12:eaav8075. https://doi.org/10.1126/scitranslmed.aav8075

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bader JM, Albrecht V, Mann M (2023) MS-based proteomics of body fluids: the end of the beginning. Mol Cell Proteomics 22:100577. https://doi.org/10.1016/j.mcpro.2023.100577

Article  PubMed  PubMed Central  CAS  Google Scholar 

Barash U, Rangappa S, Mohan CD, Vishwanath D, Boyango I, Basappa B, Vlodavsky I, Rangappa KS (2021) New heparanase-inhibiting triazolo-thiadiazoles attenuate primary tumor growth and metastasis. Cancers (Basel) 13:2959. https://doi.org/10.3390/cancers13122959

Article  PubMed  CAS  Google Scholar 

Beauvais DM, Ell BJ, McWhorter AR, Rapraeger AC (2009) Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor. J Exp Med 206:6910–7705. https://doi.org/10.1084/jem.20081278

Article  CAS  Google Scholar 

Bertrand J, Bollmann M (2019) Soluble syndecans: biomarkers for diseases and therapeutic options. Br J Pharmacol 176:67–81. https://doi.org/10.1111/bph.14397

Article  PubMed  CAS  Google Scholar 

Bishop JR, Schuksz M, Esko JD (2007) Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 446:1030–1037. https://doi.org/10.1038/nature05817

Article  PubMed  CAS  Google Scholar 

Buczek-Thomas JA, Hsia E, Rich CB, Foster JA, Nugent MA (2008) Inhibition of histone acetyltransferase by glycosaminoglycans. J Cell Biochem 105:108–120. https://doi.org/10.1002/jcb.21803

Article  PubMed  PubMed Central  CAS  Google Scholar 

Campeiro JD, Dam WA, Hayashi MAF, van den Born J (2023) Crotamine/siRNA nanocomplexes for functional downregulation of syndecan-1 in renal proximal tubular epithelial cells. Pharmaceutics 15:1576. https://doi.org/10.3390/pharmaceutics15061576

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cassinelli G, Lanzi C, Tortoreto M, Cominetti D, Petrangolini G, Favini E, Zaffaroni N, Pisano C, Penco S, Vlodavsky I, Zunino F (2013) Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models. Biochem Pharmacol 85:1424–1432. https://doi.org/10.1016/j.bcp.2013.02.023

Article  PubMed  CAS  Google Scholar 

Chen Y, Hayashida A, Bennett AE, Hollingshead SK, Park PW (2007) Streptococcus pneumoniae sheds syndecan-1 ectodomains through ZmpC, a metalloproteinase virulence factor. J Biol Chem 282:159–167. https://doi.org/10.1074/jbc.M608542200

Article  PubMed  CAS  Google Scholar 

Cui J, Jin S, Jin C, Jin Z (2020) Syndecan-1 regulates extracellular matrix expression in keloid fibroblasts via TGF-β1/Smad and MAPK signaling pathways. Life Sci 254:117326. https://doi.org/10.1016/j.lfs.2020.117326

Article  PubMed  CAS  Google Scholar 

Dedes PG, Gialeli C, Tsonis AI, Kanakis I, Theocharis AD, Kletsas D, Tzanakakis GN, Karamanos NK (2012) Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid. Biochim Biophys Acta 1820:1926–1939. https://doi.org/10.1016/j.bbagen.2012.07.013

Article  PubMed  CAS  Google Scholar 

Deng Y, Foley EM, Gonzales JC, Gordts PL, Li Y, Esko JD (2012) Shedding of syndecan-1 from human hepatocytes alters very low density lipoprotein clearance. Hepatology 55:277–286. https://doi.org/10.1002/hep.24626

Article  PubMed  CAS  Google Scholar 

Derkacz A, Olczyk P, Jura-Półtorak A, Olczyk K, Komosinska-Vassev K (2021) The diagnostic usefulness of circulating profile of extracellular matrix components: sulfated glycosaminoglycans (sGAG), hyaluronan (HA) and extracellular part of syndecan-1 (sCD138) in patients with Crohn’s disease and ulcerative colitis. J Clin Med 10:1722. https://doi.org/10.3390/jcm10081722

Article  PubMed  PubMed Central  CAS  Google Scholar 

Dosh L, Rappa F, Jurjus A, Karam G, Lezeik R, El Masri J, Bucchieri F, Leone A, Jurjus R (2024) The mechanism and potential therapeutic effects of cyclosporin, cyclophilin, probiotics and syndecan-1 in an animal model of inflammatory bowel disease. Pharmaceutics 16:130. https://doi.org/10.3390/pharmaceutics16010130

Article  PubMed  PubMed Central  CAS  Google Scholar 

Dudás J, Bocsi J, Fullár A, Baghy K, Füle T, Kudaibergenova S, Kovalszky I (2014) Heparin and liver heparan sulfate can rescue hepatoma cells from topotecan action. Biomed Res Int 2014:765794. https://doi.org/10.1155/2014/765794

Article  PubMed  PubMed Central  CAS  Google Scholar 

Farfán N, Orellana-Serradell O, Herrera D, Chrzanowsky D, Cubillos P, Marín G, Antonio García De Herreros A, Castellón EA, Contreras HR (2020) SNAIL expression correlates with the translocation of syndecan-1 intracellular domain into the nucleus in prostate cancer cell lines. Int J Mol Med 45:1073–1080. https://doi.org/10.3892/ijmm.2020.4488

Article  PubMed  PubMed Central  CAS  Google Scholar 

Floer M, Clausen M, Meister T, Vollenberg R, Bettenworth D, Tepasse PR (2021) Soluble syndecan-1 as marker of intestinal inflammation: a preliminary study and evaluation of a new panel of biomarkers for non-invasive prediction of active ulcerative colitis. Adv Clin Exp Med 30:655–660. https://doi.org/10.17219/acem/139040

Article  PubMed  Google Scholar 

Gong W, Liu Y, Huang B, Lei Z, Wu FH, Li D, Feng ZH, Zhang GM (2008) Recombinant CBD-HepII polypeptide of fibronectin inhibits alphavbeta3 signaling and hematogenous metastasis of tumor. Biochem Biophys Res Commun 367:144–149. https://doi.org/10.1016/j.bbrc.2007.12.110

Article  PubMed  CAS  Google Scholar 

Gonzales JC, Gordts PL, Foley EM, Esko JD (2013) Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans. J Clin Invest 123:2742–2751. https://doi.org/10.1172/JCI67398

Article  PubMed  PubMed Central  CAS  Google Scholar 

Green LR, Issa R, Albaldi F, Urwin L, Thompson R, Khalid H, Turner CE, Ciani B, Partridge LJ, Monk PN (2023) CD9 co-operation with syndecan-1 is required for a major staphylococcal adhesion pathway. mBio 14:e0148223. https://doi.org/10.1128/mbio.01482-23

Article  PubMed  CAS  Google Scholar 

Gregorich ZR, Ge Y (2014) Top-down proteomics in health and disease: challenges and opportunities. Proteomics 14:1195–1210. https://doi.org/10.1002/pmic.201300432

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gulli F, Marino M, Napodano C, Pocino K, Pandolfi F, Gasbarrini A, Rapaccini GL, Basile U (2020) Biomarkers in HCV-related mixed cryoglobulinemia patients with non-Hodgkin lymphoma. Eur Rev Med Pharmacol Sci 24:8067–8074. https://doi.org/10.26355/eurrev_202008_22490

Article