2024 Alzheimer’s disease facts and figures. Alzheimers Dement. 20, 3708–3821 (2024).

Nichols, E. et al. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health 7, e105–e125 (2022).

Article  Google Scholar 

Livingston, G. et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet 396, 413–446 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Lichtenstein A. H. et al. 2021 dietary guidance to improve cardiovascular health: a scientific statement from the American Heart Association. Circulation 144, e472–e487 (2021).

Google Scholar 

Yannakoulia, M. & Scarmeas, N. Diets. N. Engl. J. Med. 390, 2098–2106 (2024).

Article  PubMed  CAS  Google Scholar 

Sabia, S. et al. Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study. BMJ 366, l4414 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Yassine, H. N. et al. Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group. Lancet Healthy Longev. 3, e501–e512 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Scarmeas, N., Anastasiou, C. A. & Yannakoulia, M. Nutrition and prevention of cognitive impairment. Lancet Neurol. 17, 1006–1015 (2018).

Article  PubMed  Google Scholar 

Belder, C. R. S., Schott, J. M. & Fox, N. C. Preparing for disease-modifying therapies in Alzheimer’s disease. Lancet Neurol. 22, 782–783 (2023).

Article  PubMed  Google Scholar 

Tan, Z. S. The dawn of disease modification for Alzheimer’s disease: hope and peril. J. Am. Geriatr. Soc. 70, 1661–1663 (2022).

Article  PubMed  Google Scholar 

Willett, W. C. et al. Mediterranean diet pyramid: a cultural model for healthy eating. Am. J. Clin. Nutr. 61, 1402S–1406S (1995).

Article  PubMed  CAS  Google Scholar 

Martínez-Lapiscina, E. H., Clavero, P. & Toledo, E. et al. Mediterranean diet improves cognition: the PREDIMED-NAVARRA randomised trial. J. Neurol. Neurosurg. Psychiatry 84, 1318–1325 (2013).

Article  PubMed  Google Scholar 

Valls-Pedret, C. et al. Mediterranean diet and age-related cognitive decline: a randomized clinical trial. JAMA Intern. Med. 175, 1094–1103 (2015).

Article  PubMed  Google Scholar 

Knight, A. et al. The Mediterranean diet and cognitive function among healthy older adults in a 6-month randomised controlled trial: the MedLey study. Nutrients 8, 579 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Fu, J., Tan, L. J., Lee, J. E. & Shin, S. Association between the Mediterranean diet and cognitive health among healthy adults: a systematic review and meta-analysis. Front. Nutr. 9, 946361 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Appel, L. J. et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N. Engl. J. Med. 336, 1117–1124 (1997).

Article  PubMed  CAS  Google Scholar 

Sacks, F. M. et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N. Engl. J. Med. 344, 3–10 (2001).

Article  PubMed  CAS  Google Scholar 

Wengreen, H. et al. Prospective study of Dietary Approaches to Stop Hypertension- and Mediterranean-style dietary patterns and age-related cognitive change: the Cache County Study on Memory, Health and Aging. Am. J. Clin. Nutr. 98, 1263–1271 (2013).

Article  PubMed  PubMed Central  CAS  Google Scholar 

Berendsen, A. A. M. et al. The dietary approaches to stop hypertension diet, cognitive function, and cognitive decline in American older women. J. Am. Med. Dir. Assoc. 18, 427–432 (2017).

Article  PubMed  Google Scholar 

Haring, B. et al. No association between dietary patterns and risk for cognitive decline in older women with 9-year follow-up: data from the women’s health initiative memory study. J. Acad. Nutr. Diet. 116, 921–930.e1 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Shakersain, B. et al. The Nordic prudent diet reduces risk of cognitive decline in the Swedish older adults: a population-based cohort study. Nutrients 10, 229 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Nishi, S. K. et al. Mediterranean, DASH, and MIND dietary patterns and cognitive function: the 2-year longitudinal changes in an older Spanish cohort. Front. Aging Neurosci. 13, 782067 (2021).

Article  PubMed  PubMed Central  CAS  Google Scholar 

Daniel, G. D. et al. DASH diet adherence and cognitive function: multi-ethnic study of atherosclerosis. Clin. Nutr. ESPEN 46, 223–231 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Blumenthal, J. A. et al. Lifestyle and neurocognition in older adults with cognitive impairments: a randomized trial. Neurology 92, e212–e223 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Morris, M. C. et al. MIND diet slows cognitive decline with aging. Alzheimers Dement. 11, 1015–1022 (2015).

Article  PubMed  Google Scholar 

Hosking, D. E., Eramudugolla, R., Cherbuin, N. & Anstey, K. J. MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study. Alzheimers Dement. 15, 581–589 (2019).

Article  PubMed  Google Scholar 

Huang, L. et al. Mediterranean-dietary approaches to stop hypertension intervention for neurodegenerative delay (MIND) diet and cognitive function and its decline: a prospective study and meta-analysis of cohort studies. Am. J. Clin. Nutr. 118, 174–182 (2023).

Article  PubMed  Google Scholar 

Thomas, A. et al. Diet, pace of biological aging, and risk of dementia in the Framingham Heart Study. Ann. Neurol. 95, 1069–1079 (2024).

Article  PubMed  Google Scholar 

Thomas, A. et al. Association of a MIND diet with brain structure and dementia in a French population. J. Prev. Alzheimers Dis. 9, 655–664 (2022).

PubMed  CAS  Google Scholar 

Sawyer, R. P., Blair, J., Shatz, R., Manly, J. J. & Judd, S. E. Association of adherence to a MIND-style diet with the risk of cognitive impairment and decline in the REGARDS cohort. Neurology 103, e209817 (2024).

Article  PubMed  Google Scholar 

Berendsen, A. M. et al. Association of long-term adherence to the MIND diet with cognitive function and cognitive decline in American women. J. Nutr. Health Aging 22, 222–229 (2018).

Article  PubMed  CAS  Google Scholar 

Melo van Lent, D. et al. Mind diet adherence and cognitive performance in the Framingham Heart Study. J. Alzheimers Dis. 82, 827–839 (2021).

Article  PubMed  Google Scholar 

Boumenna, T. et al. MIND diet and cognitive function in Puerto Rican older adults. J. Gerontol. A Biol. Sci. Med. Sci. 77, 605–613 (2022).

Article  PubMed  Google Scholar 

Barnes, L. L. et al. Trial of the MIND diet for prevention of cognitive decline in older persons. N. Engl. J. Med. 389, 602–611 (2023).

Article  PubMed  PubMed Central  CAS  Google Scholar 

Zhang, X. et al. Diet quality, gut microbiota, and microRNAs associated with mild cognitive impairment in middle-aged and elderly Chinese population. Am. J. Clin. Nutr. 114, 429–440 (2021).

Article  PubMed