Bhattarai PY, Kim G, Bhandari D, Shrestha P, Choi HS (2023) Regulation of m(6)A Methylome in Cancer: Mechanisms, Implications, and Therapeutic Strategies. 13
Chen PK, Tang KT (2024) The NLRP3 inflammasome as a pathogenic player showing therapeutic potential in rheumatoid arthritis and its comorbidities. Narrative Rev 25
Cui L, Weiyao J, Chenghong S, Limei L, Xinghua Z, Bo Y, Xiaozheng D, Haidong W (2022) Rheumatoid arthritis and mitochondrial homeostasis: the crossroads of metabolism and immunity. Front Med 9:1017650
Falconer J, Murphy AN, Young SP, Clark AR, Tiziani S, Guma M, Buckley CD (2018) Review: Synovial Cell Metabolism and Chronic Inflammation in Rheumatoid Arthritis. Arthritis & rheumatology (Hoboken, NJ) 70:984–999
Fan D, Xia Y, Lu C, Ye Q, Xi X, Wang Q, Wang Z, Wang C, Xiao C (2020) Regulatory Role of the RNA N(6)-Methyladenosine modification in Immunoregulatory cells and Immune-related bone homeostasis Associated with Rheumatoid Arthritis. Front cell Dev Biology 8:627893
Gao J, Zhang H, Yang Y, Tao J (2023) Therapeutic potential of targeting the NLRP3 inflammasome in rheumatoid arthritis. Inflammation 46:835–852
Article PubMed CAS Google Scholar
Gravallese EM, Firestein GS (2023) Rheumatoid arthritis - common origins, divergent mechanisms. N Engl J Med 388:529–542
Article PubMed CAS Google Scholar
Guo C, Fu R, Wang S, Huang Y, Li X, Zhou M, Zhao J, Yang N (2018) NLRP3 inflammasome activation contributes to the pathogenesis of rheumatoid arthritis. Clin Exp Immunol 194:231–243
Article PubMed PubMed Central CAS Google Scholar
Jiang H, Cao K, Fan C, Cui X, Ma Y, Liu J (2021) Transcriptome-wide high-throughput m6A sequencing of Differential m6A methylation patterns in the Human Rheumatoid Arthritis Fibroblast-Like synoviocytes Cell Line MH7A. J Inflamm Res 14:575–586
Article PubMed PubMed Central Google Scholar
Lan J, Xu B, Shi X, Pan Q, Tao Q (2022) WTAP-mediated N(6)-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy. Cell Mol Biol Lett 27:51
Article PubMed PubMed Central CAS Google Scholar
Lin X, Chen J, Tao C, Luo L, He J, Wang Q (2023) Osthole regulates N6-methyladenosine-modified TGM2 to inhibit the progression of rheumatoid arthritis and associated interstitial lung disease. MedComm 4:e219
Article PubMed PubMed Central CAS Google Scholar
Liu X, Zhang G, Liu L, Xiong G, Liu J, Wei W (2024) USP2 promotes the proliferation and inflammation of Fibroblast-Like Synovial cells in rheumatoid arthritis through deubiquitination of TRAF2. Biochemical genetics
Nygaard G, Firestein GS (2020) Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes. 16:316–333
Qi L, Hu H, Wang Y, Hu H, Wang K, Li P, Yin J, Shi Y, Wang Y, Zhao Y, Lyu H, Feng M, Xue M, Li X, Li Y, Yan S (2022) New insights into the central sympathetic hyperactivity post-myocardial infarction: roles of METTL3-mediated m6A methylation. J Cell Mol Med 26:1264–1280
Article PubMed PubMed Central CAS Google Scholar
Qu Z, Zhou J (2020) Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1β immune pathway. 6
Wang LJ, Xue Y, Li H, Huo R, Yan Z, Wang J, Xu H, Wang J, Cao Y, Zhao JZ (2020) Wilms’ tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation. 24:4981–4991
Wang Y, Li L, Li J, Zhao B, Huang G, Li X, Xie Z, Zhou Z (2021) The emerging role of m6A modification in regulating the Immune System and Autoimmune diseases. Front cell Dev Biology 9:755691
Wu S, Li XF, Wu YY, Yin SQ, Huang C, Li J (2021) N(6) -Methyladenosine and rheumatoid arthritis: a Comprehensive Review. Front Immunol 12:731842
Article PubMed PubMed Central CAS Google Scholar
Xhemalçe B (2021) Biological functions of RNA modifications. Brief Funct Genomics 20:75–76
Article PubMed PubMed Central Google Scholar
Zhao C, Gu Y, Zeng X, Wang J (2018) NLRP3 inflammasome regulates Th17 differentiation in rheumatoid arthritis. Clin Immunol (Orlando Fla) 197:154–160
Comments (0)