Efficacy of different biologics for treating chronic rhinosinusitis with nasal polyps: a network meta-analysis

Fokkens WJ, Lund VJ, Hopkins C et al (2020) European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology. https://doi.org/10.4193/Rhin20.600

Article  PubMed  Google Scholar 

Wang XD, Zheng M, Lou HF et al (2016) An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011. Allergy 71(8):1170–1180. https://doi.org/10.1111/all.12874

Article  CAS  PubMed  Google Scholar 

Liu Z, Yao Y, Xie H et al (2024) Visual and bibliometric analysis of chronic rhinosinusitis and nasal polyps. J Allergy Clin Immunol Glob. https://doi.org/10.1016/j.jacig.2024.100211

Article  PubMed  PubMed Central  Google Scholar 

Gong X, Fu Y, Zhou L et al (2024) Decoding chronic rhinosinusitis: a metabolomics-based approach. Int Forum Allergy Rhinol. https://doi.org/10.1002/alr.23331

Article  PubMed  Google Scholar 

Behnke J, Dundervill C, Al-Asadi Z, Shahid M, Ramadan HH, Makary CA (2024) Gender differences in adults with chronic rhinosinusitis: a scoping review. Otolaryngol Head Neck Surg. https://doi.org/10.1002/ohn.663

Article  PubMed  Google Scholar 

Hong HY, Chen TY, Yang QT et al (2023) Chinese expert consensus on the use of biologics in patients with chronic Rhinosinusitis (2022, Zhuhai). ORL J Otorhinolaryngol Relat Spec 85(3):128–140. https://doi.org/10.1159/000529918

Article  PubMed  Google Scholar 

Cergan R, Berghi ON, Dumitru M, Vrinceanu D, Manole F, Serboiu CS (2023) Biologics for chronic rhinosinusitis-a modern option for therapy. Life (Basel). 13(11):2165. https://doi.org/10.3390/life13112165

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bai J, Tan BK, Kato A (2024) Endotypic heterogeneity and pathogenesis in chronic rhinosinusitis. Curr Opin Allergy Clin Immunol 24(1):1–8. https://doi.org/10.1097/ACI.0000000000000954

Article  CAS  PubMed  Google Scholar 

Kato A, Peters AT, Stevens WW, Schleimer RP, Tan BK, Kern RC (2022) Endotypes of chronic rhinosinusitis: relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches. Allergy 77(3):812–826. https://doi.org/10.1111/all.15074

Article  PubMed  Google Scholar 

Tsuda T, Suzuki M, Kato Y et al (2024) The current findings in eosinophilic chronic rhinosinusitis. Auris Nasus Larynx 51(1):51–60. https://doi.org/10.1016/j.anl.2023.08.002

Article  PubMed  Google Scholar 

Wang X, Zhang N, Bo M et al (2016) Diversity of TH cytokine profiles in patients with chronic rhinosinusitis: a multicenter study in Europe, Asia, and Oceania. J Allergy Clin Immunol 138(5):1344–1353. https://doi.org/10.1016/j.jaci.2016.05.041

Article  CAS  PubMed  Google Scholar 

Guo CL, Liu FF, Wang DY, Liu Z (2023) Type 2 biomarkers for the indication and response to biologics in CRSwNP. Curr Allergy Asthma Rep 23(12):703–713. https://doi.org/10.1007/s11882-023-01114-w

Article  CAS  PubMed  Google Scholar 

Huang Y, Zhang N, Bachert C (2023) Innovative treatments for severe uncontrolled chronic rhinosinusitis with nasal polyps. Expert Rev Clin Immunol 19(8):837–845. https://doi.org/10.1080/1744666X.2023.2206120

Article  CAS  PubMed  Google Scholar 

Haloob N, Karamali K, Hopkins C (2023) The role of biologics in the treatment of chronic rhinosinusitis. BioDrugs 37(4):477–487. https://doi.org/10.1007/s40259-023-00602-9

Article  PubMed  Google Scholar 

Kim SD, Cho KS (2023) Treatment strategy of uncontrolled chronic rhinosinusitis with nasal polyps: a review of recent evidence. Int J Mol Sci 24(5):5015. https://doi.org/10.3390/ijms24055015

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement [J]. PLoS Med 6(7):e1000097

Article  PubMed  PubMed Central  Google Scholar 

Hutton B, Salanti G, Caldwell DM et al (2015) The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med 162(11):777–784. https://doi.org/10.7326/M14-2385

Article  PubMed  Google Scholar 

Cumpston M, Li T, Page MJ et al (2019) Updated guidance for trusted systematic reviews: a new edition of the cochrane handbook for systematic reviews of interventions. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.ED000142

Article  PubMed  PubMed Central  Google Scholar 

Fahmy O, Fahmy UA, Alhakamy NA, Khairul-Asri MG (2021) Single-port versus multiple-port robot-assisted radical prostatectomy: a systematic review and meta-analysis. J Clin Med 10(24):5723. https://doi.org/10.3390/jcm10245723

Article  PubMed  PubMed Central  Google Scholar 

Chaimani A, Higgins JP, Mavridis D, Spyridonos P, Salanti G (2013) Graphical tools for network meta-analysis in STATA. PLoS ONE 8(10):e76654. https://doi.org/10.1371/journal.pone.0076654

Article  CAS  PubMed  PubMed Central  Google Scholar 

Salanti G, Ades AE, Ioannidis JP (2011) Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol 64(2):163–171. https://doi.org/10.1016/j.jclinepi.2010.03.016

Article  PubMed  Google Scholar 

Chaimani A, Salanti G (2012) Using network meta-analysis to evaluate the existence of small-study effects in a network of interventions. Res Synth Methods 3(2):161–176. https://doi.org/10.1002/jrsm.57

Article  PubMed  Google Scholar 

Tversky J, Lane AP, Azar A (2021) Benralizumab effect on severe chronic rhinosinusitis with nasal polyps (CRSwNP): a randomized double-blind placebo-controlled trial. Clin Exp Allergy 51(6):836–844. https://doi.org/10.1111/cea.13852

Article  CAS  PubMed  Google Scholar 

Canonica GW, Harrison TW, Chanez P et al (2022) Benralizumab improves symptoms of patients with severe, eosinophilic asthma with a diagnosis of nasal polyposis. Allergy 77(1):150–161. https://doi.org/10.1111/all.14902

Article  CAS  PubMed  Google Scholar 

Takabayashi T, Asaka D, Okamoto Y et al (2021) A phase II, multicenter, randomized, placebo-controlled study of Benralizumab, a Humanized anti-IL-5R alpha monoclonal antibody, in patients with eosinophilic chronic rhinosinusitis. Am J Rhinol Allergy 35(6):861–870. https://doi.org/10.1177/19458924211009429

Article  PubMed  Google Scholar 

Bachert C, Han JK, Desrosiers MY et al (2022) Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: A randomized, placebo-controlled trial. J Allergy Clin Immunol 149(4):1309-1317.e12. https://doi.org/10.1016/j.jaci.2021.08.030

Article  CAS  PubMed  Google Scholar 

Bachert C, Han JK, Desrosiers M, et al. Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials [published correction appears in Lancet. 2019 Nov 2;394(10209):1618]. Lancet.;394(10209):1638–1650. https://doi.org/10.1016/S0140-6736(19)31881-1.

Bachert C, Hellings PW, Mullol J et al (2020) Dupilumab improves health-related quality of life in patients with chronic rhinosinusitis with nasal polyposis. Allergy 75(1):148–157. https://doi.org/10.1111/all.13984

Article  CAS  PubMed  Google Scholar 

Boguniewicz M, Beck LA, Sher L et al (2021) Dupilumab improves asthma and sinonasal outcomes in adults with moderate to severe atopic dermatitis. J Allergy Clin Immunol Pract 9(3):1212-1223.e6. https://doi.org/10.1016/j.jaip.2020.12.059

Article  PubMed  Google Scholar 

Canonica GW, Bourdin A, Peters AT et al (2022) Dupilumab demonstrates rapid onset of response across three type 2 inflammatory diseases. J Allergy Clin Immunol Pract 10(6):1515–1526. https://doi.org/10.1016/j.jaip.2022.02.026

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