Breast-conserving surgery versus modified radical mastectomy in T1-2N3M0 stage breast cancer: a propensity score matching analysis

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.

Article  PubMed  Google Scholar 

Al-Ghazal SK, Fallowfield L, Blamey RW. Comparison of psychological aspects and patient satisfaction following breast conserving surgery, simple mastectomy and breast reconstruction. Eur J Cancer. 2000;36:1938–43.

Article  CAS  PubMed  Google Scholar 

van Dongen JA, Voogd AC, Fentiman IS, Legrand C, Sylvester RJ, Tong D, et al. Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: european organization for research and treatment of cancer 10801 trial. J Natl Cancer Inst. 2000;92:1143–50.

Article  PubMed  Google Scholar 

Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347:1233–41.

Article  PubMed  Google Scholar 

Veronesi U, Cascinelli N, Mariani L, Greco M, Saccozzi R, Luini A, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347:1227–32.

Article  PubMed  Google Scholar 

van Maaren MC, de Munck L, de Bock GH, Jobsen JJ, van Dalen T, Linn SC, et al. 10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study. Lancet Oncol. 2016;17:1158–70.

Article  PubMed  Google Scholar 

Fisher B, Bauer M, Margolese R, Poisson R, Pilch Y, Redmond C, et al. Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med. 1985;312:665–73.

Article  CAS  PubMed  Google Scholar 

Cabioglu N, Ozmen V, Kaya H, Tuzlali S, Igci A, Muslumanoglu M, et al. Increased lymph node positivity in multifocal and multicentric breast cancer. J Am Coll Surg. 2009;208:67–74.

Article  PubMed  Google Scholar 

Chen K, Liu J, Li S, Jacobs L. Development of nomograms to predict axillary lymph node status in breast cancer patients. BMC Cancer. 2017;17:561.

Article  PubMed  PubMed Central  Google Scholar 

Kuru B, Camlibel M, Dinc S, Gulcelik MA, Alagol H. Prognostic significance of axillary node and infraclavicular lymph node status after mastectomy. Eur J Surg Oncol. 2003;29:839–44.

Article  CAS  PubMed  Google Scholar 

Brito RA, Valero V, Buzdar AU, Booser DJ, Ames F, Strom E, et al. Long-term results of combined-modality therapy for locally advanced breast cancer with ipsilateral supraclavicular metastases: the university of texas anderson cancer center experience. J Clin Oncol. 2001;19:628–33.

Article  CAS  PubMed  Google Scholar 

Park HJ, Shin KH, Cho KH, Park IH, Lee KS, Ro J, et al. Outcomes of positron emission tomography-staged clinical N3 breast cancer treated with neoadjuvant chemotherapy, surgery, and radiotherapy. Int J Radiat Oncol Biol Phys. 2011;81:e689–95.

Article  PubMed  Google Scholar 

Amin MB, Greene FL, Edge SB, Compton CC, Gershenwald JE, Brookland RK, et al. The Eighth AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more “personalized” approach to cancer staging. CA Cancer J Clin. 2017. https://doi.org/10.3322/caac.21388.

Article  PubMed  PubMed Central  Google Scholar 

Ai X, Liao X, Li J, Tang P, Jiang J. Clinical outcomes of N3 breast cancer: a real-world study of a single institution and the US surveillance, epidemiology, and end results (SEER) database. Cancer Manag Res. 2020;12:5331–43.

Article  PubMed  PubMed Central  Google Scholar 

Wang J, Chen L, Nie Y, Wu W, Yao Y. Nomogram for predicting the overall survival of patients with breast cancer with pathologic nodal status N3. Clin Breast Cancer. 2020;20:e778–85.

Article  PubMed  Google Scholar 

Seo MJ, Lee JJ, Kim HO, Chae SY, Park SH, Ryu JS, et al. Detection of internal mammary lymph node metastasis with (18)F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with stage III breast cancer. Eur J Nucl Med Mol Imaging. 2014;41:438–45.

Article  PubMed  Google Scholar 

Melly L, Jansens JL, Kalscheuer G, Belhaj A, Rondelet B. Robotic lymphadenectomy of an internal mammary lymph node metastasis. Acta Chir Belg. 2018;118:320–1.

Article  PubMed  Google Scholar 

Thorsen LB, Offersen BV, Dano H, Berg M, Jensen I, Pedersen AN, et al. DBCG-IMN: a population-based cohort study on the effect of internal mammary node irradiation in early node-positive breast cancer. J Clin Oncol. 2016;34:314–20.

Article  PubMed  Google Scholar 

Lv M, Li J, Guo H, Wang C, Tian P, Ma Y, et al. Impact of Ipsilateral supraclavicular lymph node dissection (ISLND) for breast cancer patients and a nomogram for predicting ipsilateral supraclavicular pathological complete response (ispCR). Ann Surg Oncol. 2021;28:5098–109.

Article  PubMed  Google Scholar 

Braunstein LZ, Galland-Girodet S, Goldberg S, Warren LE, Sadek BT, Shenouda MN, et al. Long-term outcomes among breast cancer patients with extensive regional lymph node involvement: implications for locoregional management. Breast Cancer Res Treat. 2015;154:633–9.

Article  PubMed  Google Scholar 

Chen K, Liu J, Zhu L, Su F, Song E, Jacobs LK. Comparative effectiveness study of breast-conserving surgery and mastectomy in the general population: a NCDB analysis. Oncotarget. 2015;6:40127–40.

Article  PubMed  PubMed Central  Google Scholar 

Wang J, Deng JP, Sun JY, Dong Y, Zhang WW, He ZY, et al. Noninferior outcome after breast-conserving treatment compared to mastectomy in breast cancer patients with four or more positive lymph nodes. Front Oncol. 2019;9:143.

Article  PubMed  PubMed Central  Google Scholar 

Jiao Y, Guo X, Lv Q. Options of locoregional therapy for primary foci of breast cancer influence the rate of nonregional lymph node metastasis in N2–N3 status patients: a SEER database analysis. Breast Cancer. 2023;30:647–56.

Article  PubMed  Google Scholar 

Abdulkarim BS, Cuartero J, Hanson J, Deschenes J, Lesniak D, Sabri S. Increased risk of locoregional recurrence for women with T1–2N0 triple-negative breast cancer treated with modified radical mastectomy without adjuvant radiation therapy compared with breast-conserving therapy. J Clin Oncol. 2011;29:2852–8.

Article  PubMed  PubMed Central  Google Scholar 

Li H, Chen Y, Wang X, Tang L, Guan X. T1–2N0M0 triple-negative breast cancer treated with breast-conserving therapy has better survival compared to mastectomy: a SEER population-based retrospective analysis. Clin Breast Cancer. 2019;19:e669–82.

Article  PubMed  Google Scholar 

Guo L, Xie G, Wang R, Yang L, Sun L, Xu M, et al. Local treatment for triple-negative breast cancer patients undergoing chemotherapy: breast-conserving surgery or total mastectomy? BMC Cancer. 2021;21:717.

Article  PubMed  PubMed Central  Google Scholar 

Wang SE, Sun YD, Zhao SJ, Wei F, Yang G. Breast conserving surgery (BCS) with adjuvant radiation therapy showed improved prognosis compared with mastectomy for early staged triple negative breast cancer patients running title: BCS had better prognosis than mastectomy for early TNBC patients. Math Biosci Eng. 2019;17:92–104.

Article  PubMed  Google Scholar 

Murthy SM, Goldschmidt RA, Rao LN, Ammirati M, Buchmann T, Scanlon EF. The influence of surgical trauma on experimental metastasis. Cancer. 1989;64:2035–44.

Article  CAS  PubMed  Google Scholar 

Bogden AE, Moreau JP, Eden PA. Proliferative response of human and animal tumours to surgical wounding of normal tissues: onset, duration and inhibition. Br J Cancer. 1997;75:1021–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abramovitch R, Marikovsky M, Meir G, Neeman M. Stimulation of tumour growth by wound-derived growth factors. Br J Cancer. 1999;79:1392–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lacy AM, Garcia-Valdecasas JC, Delgado S, Castells A, Taura P, Pique JM, et al. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet. 2002;359:2224–9.

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