Dillekås H, Rogers MS, Straume O. Are 90% of deaths from cancer caused by metastases? Cancer Med. 2019;8:5574–6.
Article PubMed PubMed Central Google Scholar
Fidler IJ. The pathogenesis of cancer metastasis: the’seed and soil’hypothesis revisited. Nat Rev Cancer. 2003;3:453–8.
Article CAS PubMed Google Scholar
Cacho-Díaz B, García-Botello DR, Wegman-Ostrosky T, Reyes-Soto G, Ortiz-Sánchez E, Herrera-Montalvo LA. Tumor microenvironment differences between primary tumor and brain metastases. J Transl Med. 2020;18:1–12.
Article PubMed PubMed Central Google Scholar
Baghban R, Roshangar L, Jahanban-Esfahlan R, Seidi K, Ebrahimi-Kalan A, Jaymand M, Kolahian S, Javaheri T, Zare P. Tumor microenvironment complexity and therapeutic implications at a glance. Cell Communication and Signaling. 2020;18:1–19.
Anderson NM, Simon MC. The tumor microenvironment. Curr Biol. 2020;30:R921–5.
Article CAS PubMed PubMed Central Google Scholar
Meurette O, Mehlen P. Notch signaling in the tumor microenvironment. Cancer Cell. 2018;34:536–48.
Article CAS PubMed Google Scholar
Conciatori F, Bazzichetto C, Falcone I, Pilotto S, Bria E, Cognetti F, Milella M, Ciuffreda L. Role of mTOR signaling in tumor microenvironment: an overview. Int J Mol Sci. 2018;19:2453.
Article PubMed PubMed Central Google Scholar
Patel S, Alam A, Pant R, Chattopadhyay S. Wnt signaling and its significance within the tumor microenvironment: novel therapeutic insights. Front Immunol. 2019;10:2872.
Article CAS PubMed PubMed Central Google Scholar
Terceiro LE, Edechi CA, Ikeogu NM, Nickel BE, Hombach-Klonisch S, Sharif T, Leygue E, Myal Y. The breast tumor microenvironment: A key player in metastatic spread. Cancers. 2021;13:4798.
Article CAS PubMed PubMed Central Google Scholar
Paskeh MDA, Entezari M, Mirzaei S, Zabolian A, Saleki H, Naghdi MJ, Sabet S, Khoshbakht MA, Hashemi M, Hushmandi K. Emerging role of exosomes in cancer progression and tumor microenvironment remodeling. J Hematol Oncol. 2022;15:1–39.
Yang E, Wang X, Gong Z, Yu M, Wu H, Zhang D. Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression. Signal Transduct Target Ther. 2020;5:242.
Article PubMed PubMed Central Google Scholar
Zhang Y, Liu Y, Liu H, Tang WH. Exosomes: biogenesis, biologic function and clinical potential. Cell Biosci. 2019;9:1–18.
Zhang L, Yu D. Exosomes in cancer development, metastasis, and immunity. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer. 2019;1871:455–68.
Article CAS PubMed Google Scholar
Kalluri R. The biology and function of exosomes in cancer. J Clin Investig. 2016;126:1208–15.
Article PubMed PubMed Central Google Scholar
Hessvik NP, Llorente A. Current knowledge on exosome biogenesis and release. Cell Mol Life Sci. 2018;75:193–208.
Article CAS PubMed Google Scholar
Théry C, Zitvogel L, Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol. 2002;2:569–79.
Kim H, Kim DW, Cho J-Y. Exploring the key communicator role of exosomes in cancer microenvironment through proteomics. Proteome science. 2019;17:1–14.
Sun Z, Yang S, Zhou Q, Wang G, Song J, Li Z, Zhang Z, Xu J, Xia K, Chang Y. Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment. Mol Cancer. 2018;17:1–9.
Sun Z, Shi K, Yang S, Liu J, Zhou Q, Wang G, Song J, Li Z, Zhang Z, Yuan W. Effect of exosomal miRNA on cancer biology and clinical applications. Mol Cancer. 2018;17:1–19.
Uyama R, Nakagawa T, Hong SH, Mochizuki M, Nishimura R, Sasaki N. Establishment of four pairs of canine mammary tumour cell lines derived from primary and metastatic origin and their E-cadherin expression. Veterinary and comparative oncology. 2006;4:104–13.
Article CAS PubMed Google Scholar
Kim H-S, Lee K-H, Son KH, Shin T-J, Cho J-Y: Extracellular vesicle-mediated Transfer of miR-1 from Primary tumor Repress Metastasis Growth. bioRxiv 2023:2023.2005. 2019.541440. https://doi.org/10.1101/2023.05.19.541440.
Lee D, Lee K-H, Kim DW, Yoon S, Cho J-Y. CXCL5 inhibits excessive oxidative stress by regulating white adipocyte differentiation. Redox Biology. 2022;54:102359.
Article CAS PubMed PubMed Central Google Scholar
Wiśniewski JR, Zougman A, Nagaraj N, Mann M. Universal sample preparation method for proteome analysis. Nat Methods. 2009;6:359–62.
Lee D, Kim DW, Yoon S, Nam A-R, Lee K-H, Nam K-H, Cho S-M, Yoon Y, Cho J-Y. CXCL5 secreted from macrophages during cold exposure mediates white adipose tissue browning. J Lipid Res. 2021;62:100117.
Article CAS PubMed PubMed Central Google Scholar
Kulak NA, Pichler G, Paron I, Nagaraj N, Mann M. Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells. Nat Methods. 2014;11:319–24.
Article CAS PubMed Google Scholar
Son KH, Aldonza MBD, Nam A-R, Lee K-H, Lee J-W, Shin K-J, Kang K, Cho J-Y. Integrative mapping of the dog epigenome: Reference annotation for comparative intertissue and cross-species studies. Science Advances. 2023;9:eade3399.
Article CAS PubMed PubMed Central Google Scholar
Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W. Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. Proteomics. 2013;13:1672–86.
Article CAS PubMed Google Scholar
Neophytou CM, Panagi M, Stylianopoulos T, Papageorgis P. The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities. Cancers. 2021;13:2053.
Article CAS PubMed PubMed Central Google Scholar
Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential. Proteomics. 2017;17:1600370.
Ždralević M, Marchiq I, de Padua MMC, Parks SK, Pouysségur J. Metabolic plasiticy in cancers—distinct role of glycolytic enzymes GPI, LDHs or membrane transporters MCTs. Front Oncol. 2017;7:313.
Article PubMed PubMed Central Google Scholar
Ullrey DB, Franchi A, Pouyssegur J, Kalckar HM. Down-regulation of the hexose transport system: metabolic basis studied with a fibroblast mutant lacking phosphoglucose isomerase. Proc Natl Acad Sci. 1982;79:3777–9.
Article ADS CAS PubMed PubMed Central Google Scholar
Miao P, Sheng S, Sun X, Liu J, Huang G. Lactate dehydrogenase A in cancer: a promising target for diagnosis and therapy. IUBMB Life. 2013;65:904–10.
Article CAS PubMed Google Scholar
Feng Y, Xiong Y, Qiao T, Li X, Jia L, Han Y. Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy. Cancer Med. 2018;7:6124–36.
Article PubMed PubMed Central Google Scholar
Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, Yang J, Cheng C. CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Investig. 2011;121:1064–74.
Article CAS PubMed PubMed Central Google Scholar
Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL. Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Mol Cell Proteomics. 2013;12:2148–59.
Article CAS PubMed PubMed Central Google Scholar
Xu Y-F, Xu X, Gin A, Nshimiyimana JD, Mooers BH, Caputi M, Hannafon BN, Ding W-Q. SRSF1 regulates exosome microRNA enrichment in human cancer cells. Cell Communication and Signaling. 2020;18:1–13.
Article CAS PubMed PubMed Central Google Scholar
Murata S, Yashiroda H, Tanaka K. Molecular mechanisms of proteasome assembly. Nat Rev Mol Cell Biol. 2009;10:104–15.
Article CAS PubMed Google Scholar
Kumar Deshmukh F, Yaffe D, Olshina MA, Ben-Nissan G, Sharon M. The contribution of the 20S proteasome to proteostasis. Biomolecules. 2019;9:190.
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