aGastroenterology Department, Centro Hospitalar Vila Nova de Gaia Espinho (CHVNGE), Vila Nova de Gaia

bMEDCIDS, Faculty of Medicine, University of Porto

cCINTESIS@RISE, Faculty of Medicine, University of Porto

dGastroenterology Department, RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto) & Porto Comprehensive Cancer Centre (Porto.CCC), Porto, Portugal.

Received 26 June 2023 Accepted 29 September 2023.

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Correspondence to João Carlos Silva, MD, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal, Tel: +351 918598991; e-mail: [email protected]